Anti-CD1a antibody [NA1/34-HLK] (ab24055)
Key features and details
- Mouse monoclonal [NA1/34-HLK] to CD1a
- Suitable for: Flow Cyt
- Reacts with: Dog, Human, Monkey
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
Anti-CD1a antibody [NA1/34-HLK]
See all CD1a primary antibodies -
Description
Mouse monoclonal [NA1/34-HLK] to CD1a -
Host species
Mouse -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Dog, Human, Monkey -
Immunogen
Tissue, cells or virus corresponding to Human CD1a. Thymocytes (Human).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
Ion Exchange Chromatography -
Purification notes
Purified IgG prepared by ion exchange chromatography -
Clonality
Monoclonal -
Clone number
NA1/34-HLK -
Myeloma
NS1/1-Ag4-1 -
Isotype
IgG2a -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab24055 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use at an assay dependent concentration.
Use 10 ul of this concentration to label 10^6 cells in 100ul. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. Use 10 ul of this concentration to label 10^6 cells in 100ul. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Target
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Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. -
Tissue specificity
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. -
Sequence similarities
Contains 1 Ig-like (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. - Information by UniProt
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Database links
- Entrez Gene: 909 Human
- Omim: 188370 Human
- SwissProt: P06126 Human
- Unigene: 1309 Human
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Alternative names
- CD 1a antibody
- CD1 antibody
- CD1a antibody
see all
Datasheets and documents
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Datasheet download
References (6)
ab24055 has been referenced in 6 publications.
- Qeska V et al. Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription. PLoS One 9:e96121 (2014). Flow Cyt . PubMed: 24769532
- West JA et al. Polyclonal T-cells express CD1a in Langerhans cell histiocytosis (LCH) lesions. PLoS One 9:e109586 (2014). ICC ; Human . PubMed: 25343480
- Yoshino N et al. Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp Anim 49:97-110 (2000). PubMed: 10889948
- Galkowska H et al. Reactivity of antibodies directed against human antigens with surface markers on canine leukocytes. Vet Immunol Immunopathol 53:329-34 (1996). PubMed: 8969052
- Burrone OR & Milstein C Control of HLA-A,B,C synthesis and expression in interferon-treated cells. EMBO J 1:345-9 (1982). PubMed: 6765173
- McMichael AJ et al. A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol 9:205-10 (1979). PubMed: 376318