Overview

  • Product name
    Anti-CD1c antibody [M241]
    See all CD1c primary antibodies
  • Description
    Mouse monoclonal [M241] to CD1c
  • Host species
    Mouse
  • Tested applications
    Suitable for: IP, RIDmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    MOLT 4 cell line.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Constituent: PBS
  • Concentration information loading...
  • Purity
    Protein A/G purified
  • Clonality
    Monoclonal
  • Clone number
    M241
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab18216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution.
RID Use at an assay dependent dilution.

Target

  • Function
    Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
  • Tissue specificity
    Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
  • Sequence similarities
    Contains 1 Ig-like (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes.
  • Information by UniProt
  • Database links
  • Alternative names
    • BDCA1 antibody
    • CD1 antibody
    • CD1A antibody
    • CD1c antibody
    • CD1c antigen antibody
    • CD1C antigen c polypeptide antibody
    • CD1c molecule antibody
    • CD1C_HUMAN antibody
    • Cortical thymocyte antigen CD1C antibody
    • Differentiation antigen CD1 alpha 3 antibody
    • R7 antibody
    • T cell surface glycoprotein CD1c antibody
    • T-cell surface glycoprotein CD1c antibody
    see all

References

This product has been referenced in:
  • Duchalais E  et al. Colorectal Cancer Cells Adhere to and Migrate Along the Neurons of the Enteric Nervous System. Cell Mol Gastroenterol Hepatol 5:31-49 (2018). Read more (PubMed: 29188232) »
  • Small TN  et al. Characterization of B cells in severe combined immunodeficiency disease. Hum Immunol 25:181-93 (1989). Read more (PubMed: 2670851) »
See all 3 Publications for this product

Customer reviews and Q&As

Answer

Thank you for your inquiry.

Please excuse the delay in my answer, I was in contact with the lab that produce these antibodies.

Unfortunately, I was not told the immunogen for ab56325 and I apologize for any inconvenience this causes to you.

The immunogen for ab18216 was cells from the MOLT4 cell line and there is no further information if the epitope was mapped available. And therefore we donot not the immunogen sequence.

I am happy to confirm that the immunogen for ab96329 was a recombinant fragment, corresponding to a region within amino acids 61-258 of Human CD1b (NP_001755).

I hope this information is helpful. Please donot hesitate to contact me again with any further questions.

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up