Overview

  • Product name

    Anti-CD2 antibody [SP304]
    See all CD2 primary antibodies
  • Description

    Rabbit monoclonal [SP304] to CD2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human CD2 aa 1-250. The exact sequence is proprietary.
    Database link: P06729

  • Positive control

    • IHC-P: Human tonsil, thymus, colon, stomach, stomach adenocarcinoma, colon adenocarcinoma, lung squamous cell carcinoma, lung adenocarcinoma, uterus and cervical squamous cell carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab227698 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100.

Boil tissue section in EDTA buffer, pH 8.0 for 10 minutes followed by cooling at room temperature for 20 minutes.

Incubate with primary antibody for 10 minutes at room temperature.

Target

  • Function

    CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
  • Sequence similarities

    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD 2 antibody
    • CD2 antibody
    • CD2 antigen (p50), sheep red blood cell receptor antibody
    • CD2 antigen antibody
    • CD2 molecule antibody
    • CD2_HUMAN antibody
    • Erythrocyte receptor antibody
    • FLJ46032 antibody
    • LFA-2 antibody
    • LFA-3 receptor antibody
    • LFA2 antibody
    • LFA3 receptor antibody
    • Ly-37 antibody
    • Lymphocyte function antigen 2 antibody
    • lymphocyte-function antigen-2 antibody
    • OTTHUMP00000024366 antibody
    • Rosette receptor antibody
    • Sheep erythrocyte receptor antibody
    • SRBC antibody
    • T cell surface antigen CD2 antibody
    • T-cell surface antigen CD2 antibody
    • T-cell surface antigen T11/Leu-5 antibody
    • T-lymphocyte surface CD2 antigen antibody
    • T11 antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human tonsil tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human tonsil tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human thymus tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human colon tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human stomach tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human stomach adenocarcinoma tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human colon adenocarcinoma tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human lung squamous cell carcinoma tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human lung adenocarcinoma tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human uterus tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

  • Formalin-fixed, paraffin-embedded human cervical squamous cell carcinoma tissue stained for CD2 using ab227698 at 1/100 dilution in immunohistochemical analysis. 

References

ab227698 has not yet been referenced specifically in any publications.

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