Key features and details
- Mouse monoclonal [2H7] to CD20 (PE/DyLight™ 594)
- Suitable for: Flow Cyt
- Reacts with: Human, Non human primates
- Conjugation: PE/DyLight™ 594
- Isotype: IgG2b
Product nameAnti-CD20 antibody [2H7] (PE/DyLight™ 594)
See all CD20 primary antibodies
DescriptionMouse monoclonal [2H7] to CD20 (PE/DyLight™ 594)
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human, Non human primates
Tissue, cells or virus corresponding to Human CD20. Human tonsillar B cells.
Database link: P11836
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at +4°C. Store In the Dark.
Storage bufferpH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 99% PBS, 0.2% BSA
Concentration information loading...
Purification notesThe purity of ab187593 is >95% by SDS-PAGE.
- Anti-CD20 antibody [2H7] (PE) (ab112461)
- Anti-CD20 antibody [2H7] (PerCP) (ab114860)
- Anti-CD20 antibody [2H7] (Biotin) (ab123487)
- Anti-CD20 antibody [2H7], prediluted (PerCP/Cy5.5®) (ab155376)
- Anti-CD20 antibody [2H7] (PerCP/Cy5.5®) (ab157321)
- Anti-CD20 antibody [2H7] (PE/Cy7®) (ab234204)
- Anti-CD20 antibody [2H7] (Alexa Fluor® 700) (ab269315)
- Anti-CD20 antibody [2H7] (FITC) (ab51792)
Our Abpromise guarantee covers the use of ab187593 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 4µl for 106 cells.
in 100 μl of whole blood.
FunctionThis protein may be involved in the regulation of B-cell activation and proliferation.
Tissue specificityExpressed on B-cells.
Involvement in diseaseDefects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
Sequence similaritiesBelongs to the MS4A family.
modificationsPhosphorylated. Might be functionally regulated by protein kinase(s).
- Information by UniProt
- APY antibody
- ATOPY antibody
- B lymphocyte antigen CD20 antibody
ab187593 has not yet been referenced specifically in any publications.