Key features and details
- Rabbit polyclonal to CD20, prediluted
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CD20 antibody, prediluted
See all CD20 primary antibodies
DescriptionRabbit polyclonal to CD20, prediluted
Specificityab27092 recognises CD20.
Tested Applications & Species
Application Species IHC-PHuman WBHuman
Synthetic peptide within Human CD20 aa 250 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P11836
- BJAB WCL and tonsil.
This product is FOR RESEARCH USE ONLY. For commercial use, please contact firstname.lastname@example.org.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: Tris buffered saline, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab27092 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Note: Incubation time is 10 minute at room temperature and the staining is cytoplasmic and on the cell membrane.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionThis protein may be involved in the regulation of B-cell activation and proliferation.
Tissue specificityExpressed on B-cells.
Involvement in diseaseDefects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
Sequence similaritiesBelongs to the MS4A family.
modificationsPhosphorylated. Might be functionally regulated by protein kinase(s).
- Information by UniProt
- APY antibody
- ATOPY antibody
- B lymphocyte antigen CD20 antibody
Formalin fixed, parffin embedded human tonsil tissue slide stained with anti CD20 antibody (ab27092).
Anti-CD20 antibody (ab27093) at 1/25 dilution + Raji cell lysate
Predicted band size: 33 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
ab27092 has not yet been referenced specifically in any publications.