Key features and details
- Rabbit polyclonal to CD20, prediluted
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Product nameAnti-CD20 antibody, prediluted
See all CD20 primary antibodies
DescriptionRabbit polyclonal to CD20, prediluted
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide within Human CD20 aa 250 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P11836
- BJAB WCL and tonsil.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: Tris buffered saline, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab27092 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Note: Incubation time is 10 minute at room temperature and the staining is cytoplasmic and on the cell membrane.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionThis protein may be involved in the regulation of B-cell activation and proliferation.
Tissue specificityExpressed on B-cells.
Involvement in diseaseDefects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
Sequence similaritiesBelongs to the MS4A family.
modificationsPhosphorylated. Might be functionally regulated by protein kinase(s).
- Information by UniProt
- APY antibody
- ATOPY antibody
- B lymphocyte antigen CD20 antibody
Formalin fixed, parffin embedded human tonsil tissue slide stained with anti CD20 antibody (ab27092).
Anti-CD20 antibody (ab27093) at 1/25 dilution + Raji cell lysate
Predicted band size: 33 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
ab27092 has not yet been referenced specifically in any publications.