Overview

  • Product name

  • Description

    Rabbit polyclonal to CD200R
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Fusion protein corresponding to Human CD200R (internal sequence). (The identity of the protein fusion partner is GST; Gene Accssion: BC069661).
    Database link: Q8TD46-4

  • Positive control

    • Human thyroid cancer and prostate cancer tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab198010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.

Target

  • Function

    Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
  • Tissue specificity

    Expressed in granulocytes, monocytes, most T cells, neutrophils, basophils and a subset of NK, NKT and B cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.
  • Sequence similarities

    Belongs to the CD200R family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Post-translational
    modifications

    The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD 200R antibody
    • CD200 cell surface glycoprotein receptor antibody
    • CD200 receptor 1 antibody
    • Cd200r1 antibody
    • Cell surface glycoprotein CD200 receptor 1 antibody
    • Cell surface glycoprotein OX2 receptor 1 antibody
    • Cell surface glycoprotein OX2 receptor antibody
    • cell surface glycoprotein receptor CD200 antibody
    • CRTR 2 antibody
    • CRTR2 antibody
    • HCRTR2 antibody
    • MO2R1_HUMAN antibody
    • MOX2 receptor antibody
    • MOX2R antibody
    • OX2R antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling CD200R with ab198010 at 1/70 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue labeling CD200R with ab198010 at 1/70 dilution.

References

This product has been referenced in:

  • Sun FJ  et al. Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex. J Neuroinflammation 13:85 (2016). IHC-P ; Human . Read more (PubMed: 27095555) »
See 1 Publication for this product

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