Overview

  • Product name

  • Description

    Rabbit polyclonal to CD204
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human CD204 aa 230-272 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    KEEQVHLEQEIKGEVKVLNNITNDLRLKDWEHSQTLRNITLIQ


    Database link: P21757

  • Positive control

    • Human glioma and esophageal cancer tissues. Human colon carcinoma lysates.
  • General notes

     This product was previously labelled as Macrophage Scavenger Receptor I

     

Properties

Applications

Our Abpromise guarantee covers the use of ab217843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize actetylated LDL.
  • Tissue specificity

    Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages.
  • Sequence similarities

    Contains 1 collagen-like domain.
    Contains 1 SRCR domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD204 antibody
    • CD204 antigen antibody
    • CD24 antibody
    • Macrophage acetylated LDL receptor I and II antibody
    • Macrophage scavenger receptor 1 antibody
    • Macrophage scavenger receptor type III antibody
    • Macrophage scavenger receptor types I and II antibody
    • Msr 1 antibody
    • MSR1 antibody
    • MSRE_HUMAN antibody
    • phSR1 antibody
    • phSR2 antibody
    • SCARA 1 antibody
    • SCARA1 antibody
    • Scavenger receptor class A member 1 antibody
    • Scavenger receptor class A, member 1 antibody
    • Scavenger receptor type A antibody
    • Scvr antibody
    • SR A antibody
    • SRA antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded Human glioma tissue, labeling CD204 using ab217843 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded Human esophageal cancer tissue, labeling CD204 using ab217843 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • All lanes : Anti-CD204 antibody (ab217843) at 1/200 dilution

    Lane 1 : Human colon carcinoma lysates
    Lane 2 : rat brain lysates

    Secondary
    All lanes : goat anti-rabbit IgG antibody (H+L) HRP-conjugated at 1/3000 dilution

    Developed using the ECL technique.

    Predicted band size: 41 kDa
    Observed band size: 41 kDa



    12% gel

References

ab217843 has not yet been referenced specifically in any publications.

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