Anti-CD28 antibody [PV-1] (ab25234)
Key features and details
- Armenian hamster monoclonal [PV-1] to CD28
- Isotype: IgG
Overview
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Product name
Anti-CD28 antibody [PV-1]
See all CD28 primary antibodies -
Description
Armenian hamster monoclonal [PV-1] to CD28 -
Host species
Armenian hamster -
Specificity
ab25234 recognises Murine CD28. -
Immunogen
The details of the immunogen for this antibody are not available.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 8.20
Constituent: 100% Borate buffered saline -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
PV-1 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Target
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Function
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. -
Tissue specificity
Expressed in T-cells and plasma cells, but not in less mature B-cells. -
Sequence similarities
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
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Alternative names
- CD 28 antibody
- CD28 antibody
- CD28 antigen antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab25234 has been referenced in 5 publications.
- Wang J et al. PDL1 Fusion Protein Protects Against Experimental Cerebral Malaria via Repressing Over-Reactive CD8+ T Cell Responses. Front Immunol 9:3157 (2018). PubMed: 30693001
- Meyer Zu Horste G et al. Predicting the Response to Intravenous Immunoglobulins in an Animal Model of Chronic Neuritis. PLoS One 11:e0164099 (2016). Flow Cyt . PubMed: 27711247
- Mascanfroni ID et al. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-a. Nat Med 21:638-46 (2015). PubMed: 26005855
- Fischer N et al. Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG. Nat Commun 6:6113 (2015). PubMed: 25672245
- Quintana FJ et al. Aiolos promotes TH17 differentiation by directly silencing Il2 expression. Nat Immunol 13:770-7 (2012). PubMed: 22751139