Overview

  • Product name

  • Description

    Mouse polyclonal to CD300a
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length protein corresponding to Human CD300a.

  • Positive control

    • Human spleen tissue lysate, CD300a transfected 293T cell lysate.
  • General notes

     This product was previously labelled as CD300 antigen

     

Properties

Applications

Our Abpromise guarantee covers the use of ab88873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 33 kDa.

Target

  • Function

    Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
  • Tissue specificity

    Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
  • Sequence similarities

    Belongs to the CD300 family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Post-translational
    modifications

    Phosphorylated on tyrosine.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD300 antigen-like family member A antibody
    • CD300a antibody
    • CD300a antigen antibody
    • CD300a molecule antibody
    • CLM-8 antibody
    • CLM8_HUMAN antibody
    • CMRF 35 H9 antibody
    • CMRF-35-H9 antibody
    • CMRF35-H antibody
    • CMRF35-H9 antibody
    • CMRF35-like molecule 8 antibody
    • CMRF35H antibody
    • CMRF35H leukocyte immunoglobulin like receptor antibody
    • CMRF35H9 antibody
    • IgSF12 antibody
    • Immunoglobulin superfamily member 12 antibody
    • Inhibitory receptor protein 60 antibody
    • IRC1 antibody
    • IRC1/IRC2 antibody
    • IRC2 antibody
    • IRp60 antibody
    • Leukocyte membrane antigen antibody
    • Mast cell derived paired immunoglobulin like receptor 1 antibody
    • NK inhibitory receptor antibody
    • Polymeric immunoglobulin receptor 4 antibody
    see all

Images

  • Anti-CD300a antibody (ab88873) at 1 µg/ml + human spleen tissue lysate at 50 µg

    Predicted band size: 33 kDa
    Observed band size: 60 kDa
    why is the actual band size different from the predicted?

  • All lanes : Anti-CD300a antibody (ab88873) at 1 µg/ml

    Lane 1 : CD300 antigen transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size: 33 kDa
    Observed band size: 33 kDa
    Additional bands at: 19 kDa. We are unsure as to the identity of these extra bands.

References

ab88873 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab88873.
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