Anti-CD32A antibody (ab167381)

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Overview

  • Product name

    Anti-CD32A antibody
    See all CD32A primary antibodies

  • Description

    Mouse polyclonal to CD32A

  • Host species

    Mouse

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Full length protein, corresponding to amino acids 1-316 of Human CD32A, isoform 2 (AAH20823.1).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • CD32A transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab167381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa.

Target

  • Function

    Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

  • Tissue specificity

    Found on monocytes, neutrophils and eosinophil platelets.

  • Sequence similarities

    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

  • Post-translational
    modifications

    Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • CD32 antibody
      • CD32 antigen antibody
      • CDw32 antibody
      • Fc fragment of IgG, low affinity IIa, receptor (CD32) antibody
      • Fc fragment of IgG, low affinity IIa, receptor for (CD32) antibody
      • Fc gamma RII a antibody
      • Fc gamma RIIa antibody
      • Fc-gamma RII-a antibody
      • Fc-gamma-RIIa antibody
      • FCG2 antibody
      • FCG2A_HUMAN antibody
      • FcGR antibody
      • FCGR2 antibody
      • FCGR2A antibody
      • FCGR2A1 antibody
      • FcRII a antibody
      • FcRII-a antibody
      • IGFR2 antibody
      • IgG Fc receptor II a antibody
      • IgG Fc receptor II-a antibody
      • Immunoglobulin G Fc receptor II antibody
      • low affinity immunoglobulin gamma Fc region receptor II a antibody
      • Low affinity immunoglobulin gamma Fc region receptor II-a antibody
      see all

    Images

    • Western blot - Anti-CD32A antibody (ab167381)
      Western blot - Anti-CD32A antibody (ab167381)
      All lanes : Anti-CD32A antibody (ab167381) at 1 µg/ml

      Lane 1 : CD32A transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 15 µl per lane.

      Secondary
      All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary at 1/2500 dilution

      Predicted band size: 35 kDa

    References

    This product has been referenced in:

    • Kozicky LK  et al. IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an Fc?RIIA Disease-Associated Gene Variant. Front Immunol 9:2676 (2018). Read more (PubMed: 30515163) »
    See 1 Publication for this product

    Publishing research using ab167381? Please let us know so that we can cite the reference in this datasheet.

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