Anti-CD32A antibody (ab167381)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-CD32A antibody
See all CD32A primary antibodies -
DescriptionMouse polyclonal to CD32A
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Host speciesMouse
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
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Immunogen
Full length protein, corresponding to amino acids 1-316 of Human CD32A, isoform 2 (AAH20823.1).
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Positive control
- CD32A transfected 293T cell lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.20
Constituent: 99% PBS -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab167381 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. |
Target
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FunctionBinds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
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Tissue specificityFound on monocytes, neutrophils and eosinophil platelets.
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Sequence similaritiesContains 2 Ig-like C2-type (immunoglobulin-like) domains.
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Post-translational
modificationsPhosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. -
Cellular localizationCell membrane.
- Information by UniProt
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Database links
- Entrez Gene: 2212 Human
- Omim: 146790 Human
- SwissProt: P12318 Human
- Unigene: 352642 Human
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Alternative names
- CD32 antibody
- CD32 antigen antibody
- CDw32 antibody
see all
Images
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Western blot - Anti-CD32A antibody (ab167381)All lanes : Anti-CD32A antibody (ab167381) at 1 µg/ml
Lane 1 : CD32A transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary at 1/2500 dilution
Predicted band size: 35 kDa
Protocols
Datasheets and documents
References
This product has been referenced in:
- Kozicky LK et al. IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an Fc?RIIA Disease-Associated Gene Variant. Front Immunol 9:2676 (2018). Read more (PubMed: 30515163) »
