Key features and details
- Rabbit polyclonal to CD38
- Suitable for: IHC-P, WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CD38 antibody
See all CD38 primary antibodies
DescriptionRabbit polyclonal to CD38
Tested applicationsSuitable for: IHC-P, WB, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Cynomolgus monkey
- IHC-P: Human tonsil, rectum and tonsil tissue. WB: Daudi cell lysate. CD38 overexpression HEK-293T cell lysate. ICC/IF: A549 cells.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab244390 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml.|
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100.
FunctionSynthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Tissue specificityExpressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Sequence similaritiesBelongs to the ADP-ribosyl cyclase family.
Developmental stagePreferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
- Information by UniProt
FormThere are 2 isoforms produced by alternative splicing.
- Acute lymphoblastic leukemia cells antigen CD38 antibody
- ADP ribosyl cyclase 1 antibody
- ADP ribosyl cyclase antibody
Paraffin-embedded human rectum tissue stained for CD38 using ab244390 at 1/1000 dilution in immunohistochemical analysis.
Paraffin-embedded human prostate tissue stained for CD38 using ab244390 at 1/1000 dilution in immunohistochemical analysis.
PFA-fixed, Triton X-100 permeabilized A549 (human lung carcinoma cell line) cells stained for CD38 (green) using ab244390 at 4 µg/ml in ICC/IF.
Paraffin-embedded human tonsil tissue stained for CD38 using ab244390 at 1/1000 dilution in immunohistochemical analysis.
Paraffin-embedded human kidney tissue stained for CD38 using ab244390 at 1/1000 dilution in immunohistochemical analysis.
Low expression as expected.
Anti-CD38 antibody (ab244390) at 0.4 µg/ml + Daudi (Human Burkitt's lymphoma cell line) cell lysate
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab244390 has not yet been referenced specifically in any publications.