Overview

  • Product name

    Anti-CD39 antibody [A1] (Phycoerythrin)
    See all CD39 primary antibodies
  • Description

    Mouse monoclonal [A1] to CD39 (Phycoerythrin)
  • Host species

    Mouse
  • Conjugation

    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Specificity

    Binds to the human CD39 cell surface antigen (70-100kD)
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    PHA activated human lymphocytes.

  • General notes


    CD39 has intrinsic ecto-ATPase activity.

    Purified IgG conjugated to R. Phycoerythrin (RPE).

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Protein G affinity chromatography from tissue culture supernatant.
  • Primary antibody notes

    CD39 has intrinsic ecto-ATPase activity.
  • Clonality

    Monoclonal
  • Clone number

    A1
  • Myeloma

    NS1
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab30424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells.

Use 10µl to label 106 cells or 100µl whole blood.

 

 

 

 

ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.
  • Tissue specificity

    Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only.
  • Sequence similarities

    Belongs to the GDA1/CD39 NTPase family.
  • Post-translational
    modifications

    The N-terminus is blocked.
    Palmitoylated in the N-terminal part.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Form

    There are 3 isoforms produced by alternative splicing.
  • Alternative names

    • ATPDase antibody
    • CD 39 antibody
    • CD39 antibody
    • CD39 antigen antibody
    • DKFZp686D194 antibody
    • DKFZp686I093 antibody
    • Ecto apyrase antibody
    • Ecto ATP diphosphohydrolase antibody
    • Ecto-apyrase antibody
    • Ecto-ATP diphosphohydrolase 1 antibody
    • Ecto-ATPase 1 antibody
    • Ecto-ATPDase 1 antibody
    • Ectonucleoside triphosphate diphosphohydrolase 1 antibody
    • ENTP1_HUMAN antibody
    • ENTPD 1 antibody
    • ENTPD1 antibody
    • FLJ40921 antibody
    • FLJ40959 antibody
    • Lymphoid cell activation antigen antibody
    • NTPDase 1 antibody
    • NTPDase1 antibody
    • SPG64 antibody
    see all

References

This product has been referenced in:

  • Jandus C  et al. Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum 58:2307-17 (2008). Flow Cyt ; Human . Read more (PubMed: 18668556) »
  • Valencic E  et al. T cells stimulated in vitro have a suppressive function but do not contain only regulatory T cells. Clin Exp Immunol 150:561-6 (2007). Flow Cyt ; Human . Read more (PubMed: 17900303) »
See all 3 Publications for this product

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