Product nameAnti-CD4 + CD8 antibody [YKIX 302.9 + YCATE 55.9] (Dual color: FITC + PE)
See all CD4 + CD8 primary antibodies
DescriptionRat monoclonal [YKIX 302.9 + YCATE 55.9] to CD4 + CD8 (Dual color: FITC + PE)
ConjugationDual color: FITC + PE
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Dog
This product was produced with the following immunogens:
Tissue, cells or virus. Concanavallin A activated T cell blasts. (CloneYKIX302.9)
Fusion protein. CD8 alpha chimaeric human IgG1 Fc fusion protein. (Clone YCATE55.9)
Please note that this antibody is an oligoclonal antibody. It is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies have not only the specificity and batch-to-batch consistency of a monoclonal antibody, but also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen. This cocktail consists of: CD4 = Clone:YKIX 302.9, Isotype:IgG1, Label:FITC CD8 = Clone:YCATE 55.9, Isotype:IgG2a, Label:PE
ab34267 should be stored undiluted. It is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage instructionsShipped at 4°C. Store at +4°C. Do Not Freeze. Please see notes section.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, PBS, 5% Sucrose
Concentration information loading...
PurityProtein G purified
Clone numberYKIX 302.9 + YCATE 55.9
Our Abpromise guarantee covers the use of ab34267 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 10µl for 106 cells.|
RelevanceCD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Cellular localizationMembrane; single pass type I membrane protein.
- CD4 antigen antibody
- CD4 molecule antibody
- CD4 mut antibody
ab34267 has not yet been referenced specifically in any publications.