Overview

  • Product name

  • Description

    Rabbit polyclonal to CD42a/GP-IX
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human CD42a/GP-IX.
    Database link: P14770

  • Positive control

    • U87 cell lysate; mouse lung, spleen, liver and skeletal muscle lysates.
  • General notes

    Previously labelled as CD42a. 

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab186840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 19 kDa.
IHC-P 1/50 - 1/200.

Target

  • Function

    The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
  • Involvement in disease

    Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
  • Sequence similarities

    Contains 1 LRR (leucine-rich) repeat.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD42a antibody
    • Glycoprotein 9 antibody
    • Glycoprotein IX antibody
    • Glycoprotein IX (platelet) antibody
    • Glycoprotein IX precursor antibody
    • GP IX antibody
    • GP-IX antibody
    • GP9 antibody
    • GPIX antibody
    • GPIX_HUMAN antibody
    • Platelet glycoprotein IX antibody
    see all

Images

  • All lanes : Anti-CD42a/GP-IX antibody (ab186840) at 1/500 dilution

    Lane 1 : U87 cell lysate
    Lane 2 : mouse lung lysate
    Lane 3 : mouse spleen lysate
    Lane 4 : mouse liver lysate
    Lane 5 : mouse skeletal muscle lysate

    Predicted band size: 19 kDa

References

ab186840 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab186840.
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