Key features and details
- Rabbit monoclonal [EP5294] to CD42a/GP-IX
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CD42a/GP-IX antibody [EP5294]
See all CD42a/GP-IX primary antibodies
DescriptionRabbit monoclonal [EP5294] to CD42a/GP-IX
Tested applicationsSuitable for: WBmore details
Unsuitable for: ICC/IF,IHC-P or IP
Species reactivityReacts with: Human
Synthetic peptide within Human CD42a/GP-IX aa 50-150. The exact sequence is proprietary.
- Human platelet and Peripheral Blood Mononuclear Cell (PBMC) lysates.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Previously labelled as CD42a.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Dissociation constant (KD)KD = 3.03 x 10 -11 M Learn more about KD
Storage bufferpH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab133573 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000 - 1/50000. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).|
FunctionThe GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
Involvement in diseaseDefects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
Sequence similaritiesContains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
- Information by UniProt
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
All lanes : Anti-CD42a/GP-IX antibody [EP5294] (ab133573) at 1/10000 dilution
Lane 1 : Human platelet lysate
Lane 2 : PBMC lysate
Lysates/proteins at 10 µg per lane.
All lanes : Standard HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa
Equilibrium disassociation constant (KD)
Learn more about KD
Click here to learn more about KD
ab133573 has not yet been referenced specifically in any publications.