Overview

  • Product name

    Anti-CD42a/GP-IX antibody [GR-P] (CF405M)
    See all CD42a/GP-IX primary antibodies
  • Description

    Mouse monoclonal [GR-P] to CD42a/GP-IX (CF405M)
  • Host species

    Mouse
  • Conjugation

    CF405M. Ex: 408nm, Em: 452nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to CD42a/GP-IX.

  • Positive control

    • Human platelets in normal peripheral blood.
  • General notes

    CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.

    Previously labelled as CD42a. 

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Note: Buffer containing antibody stabilizer solution.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Monoclonal
  • Clone number

    GR-P
  • Isotype

    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab119483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 5µl for 106 cells.

ab126036 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
  • Involvement in disease

    Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
  • Sequence similarities

    Contains 1 LRR (leucine-rich) repeat.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD42a antibody
    • Glycoprotein 9 antibody
    • Glycoprotein IX antibody
    • Glycoprotein IX (platelet) antibody
    • Glycoprotein IX precursor antibody
    • GP IX antibody
    • GP-IX antibody
    • GP9 antibody
    • GPIX antibody
    • GPIX_HUMAN antibody
    • Platelet glycoprotein IX antibody
    see all

Images

  • ab119483, at 5 µl/106 cells, staining CD42a/GP-IX in Human platelets from normal Human peripheral blood cells by Flow Cytometry. Total events were used for the analysis.

References

ab119483 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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