Key features and details
- Mouse monoclonal [GR-P] to CD42a/GP-IX (PE)
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Product nameAnti-CD42a/GP-IX antibody [GR-P] (PE)
See all CD42a/GP-IX primary antibodies
DescriptionMouse monoclonal [GR-P] to CD42a/GP-IX (PE)
ConjugationPE. Ex: 488nm, Em: 575nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human
Tissue, cells or virus corresponding to Human CD42a/GP-IX.
- Human peripheral blood platelets
Previously labelled as CD42a.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
Purification notesab30399 was purified by ion exchange chromatography.
Our Abpromise guarantee covers the use of ab30399 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionThe GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
Involvement in diseaseDefects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
Sequence similaritiesContains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
- Information by UniProt
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
ab30399 has been referenced in 1 publication.
- Tehrani S et al. High-dose aspirin is required to influence plasma fibrin network structure in patients with type 1 diabetes. Diabetes Care 35:404-8 (2012). Flow Cyt ; Human . PubMed: 22148098