Overview

  • Product name
    Anti-CD42b antibody [AK2] (FITC)
    See all CD42b primary antibodies
  • Description
    Mouse monoclonal [AK2] to CD42b (FITC)
  • Host species
    Mouse
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • Human peripheral blood platelets
  • General notes


    Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Primary antibody notes
    Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets.
  • Clonality
    Monoclonal
  • Clone number
    AK2
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab30401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Use neat - 1/10. Use 10µl of the suggested working dilution to label 100µl whole blood.

 

 

 

ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Relevance
    CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.
  • Cellular localization
    Cell Membrane
  • Database links
    • Alternative names
      • Antigen CD42b alpha antibody
      • BDPLT1 antibody
      • BDPLT3 antibody
      • BSS antibody
      • CD 42b antibody
      • CD42b alpha antibody
      • CD42B antibody
      • CD42b antigen antibody
      • DBPLT3 antibody
      • GLYCOCALICIN antibody
      • Glycoprotein Ib (platelet) alpha polypeptide antibody
      • Glycoprotein Ibalpha antibody
      • GP Ib alpha antibody
      • GP1B antibody
      • GP1BA antibody
      • GPIb alpha antibody
      • GPIbA antibody
      • MGC34595 antibody
      • Platelet glycoprotein Ib alpha chain antibody
      • Platelet glycoprotein Ib alpha polypeptide antibody
      • Platelet membrane glycoprotein 1b alpha subunit antibody
      • VWDP antibody
      see all

    Images

    • Flow Cytometry - Anti-CD42b antibody [AK2] (FITC) (ab30401)
      Flow Cytometry - Anti-CD42b antibody [AK2] (FITC) (ab30401)
      FACS analysis of CD42b expressing cells in human peripheral blood platelets using ab30401.

    References

    This product has been referenced in:
    • Kumar RA  et al. Kinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates. Biophys J 85:4099-109 (2003). Read more (PubMed: 14645097) »

    See 1 Publication for this product

    Publishing research using ab30401? Please let us know so that we can cite the reference in this datasheet.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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