Anti-CD42b antibody [AK2] (FITC) (ab30401)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-CD42b antibody [AK2] (FITC)
See all CD42b primary antibodies -
DescriptionMouse monoclonal [AK2] to CD42b (FITC)
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Host speciesMouse
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ConjugationFITC. Ex: 493nm, Em: 528nm
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Tested applicationsSuitable for: Flow Cytmore details
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Species reactivityReacts with: Human
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Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- Human peripheral blood platelets
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General notes
Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C.
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Storage bufferPreservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 -
Concentration information loading... -
PurityProtein G purified
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Primary antibody notesClone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets.
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ClonalityMonoclonal
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Clone numberAK2
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IsotypeIgG1
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Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab30401 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use at an assay dependent concentration. Use neat - 1/10. Use 10µl of the suggested working dilution to label 100µl whole blood.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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Target
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RelevanceCD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.
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Cellular localizationCell Membrane
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Database links
- Entrez Gene: 2811 Human
- Omim: 606672 Human
- SwissProt: P07359 Human
- Unigene: 1472 Human
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Alternative names
- Antigen CD42b alpha antibody
- BDPLT1 antibody
- BDPLT3 antibody
see all
Images
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![Flow Cytometry - Anti-CD42b antibody [AK2] (FITC) (ab30401)](https://www.abcam.com/ps/products/30/ab30401/Images/FACS cd42bfitc.jpg)
Flow Cytometry - Anti-CD42b antibody [AK2] (FITC) (ab30401)FACS analysis of CD42b expressing cells in human peripheral blood platelets using ab30401.
Protocols
Datasheets and documents
References
This product has been referenced in:
- Kumar RA et al. Kinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates. Biophys J 85:4099-109 (2003). Read more (PubMed: 14645097) »
