Key features and details
- Mouse monoclonal [HIP1] to CD42b (PE)
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Product nameAnti-CD42b antibody [HIP1] (PE)
See all CD42b primary antibodies
DescriptionMouse monoclonal [HIP1] to CD42b (PE)
ConjugationPE. Ex: 488nm, Em: 575nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human
Human peripherial blood mononuclear cells of a patient suffering with CLL.
- Human peripheral blood platelets.
Clone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Constituent: 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Primary antibody notesClone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation.
Our Abpromise guarantee covers the use of ab90951 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 20µl for 106 cells.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
RelevanceCD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.
Cellular localizationCell Membrane
- Antigen CD42b alpha antibody
- BDPLT1 antibody
- BDPLT3 antibody
ab90951 has been referenced in 2 publications.
- Di Buduo CA et al. Modular flow chamber for engineering bone marrow architecture and function. Biomaterials 146:60-71 (2017). PubMed: 28898758
- Di Buduo CA et al. Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients. Sci Rep 6:23213 (2016). PubMed: 26987485