Overview

  • Product name

    Anti-CD42b antibody [HIP1] (Phycoerythrin)
    See all CD42b primary antibodies
  • Description

    Mouse monoclonal [HIP1] to CD42b (Phycoerythrin)
  • Host species

    Mouse
  • Conjugation

    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Human peripherial blood mononuclear cells of a patient suffering with CLL.

  • Positive control

    • Human peripheral blood platelets.
  • General notes

    Clone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, pH 7.2
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Primary antibody notes

    Clone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation.
  • Clonality

    Monoclonal
  • Clone number

    HIP1
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab90951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 20µl for 106 cells.

ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Relevance

    CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.
  • Cellular localization

    Cell Membrane
  • Database links

  • Alternative names

    • Antigen CD42b alpha antibody
    • BDPLT1 antibody
    • BDPLT3 antibody
    • BSS antibody
    • CD 42b antibody
    • CD42b alpha antibody
    • CD42B antibody
    • CD42b antigen antibody
    • DBPLT3 antibody
    • GLYCOCALICIN antibody
    • Glycoprotein Ib (platelet) alpha polypeptide antibody
    • Glycoprotein Ibalpha antibody
    • GP Ib alpha antibody
    • GP1B antibody
    • GP1BA antibody
    • GPIb alpha antibody
    • GPIbA antibody
    • MGC34595 antibody
    • Platelet glycoprotein Ib alpha chain antibody
    • Platelet glycoprotein Ib alpha polypeptide antibody
    • Platelet membrane glycoprotein 1b alpha subunit antibody
    • VWDP antibody
    see all

Images

  • ab90951, at 20µl/106 cells, staining CD42b in Human platelets from normal peripheral blood by Flow Cytometry.
  • ab90951, at 20µl/106 cells, staining CD42b in Human Platelets from normal peripheral blood by Flow Cytometry.

References

ab90951 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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