Product nameAnti-CD43 antibody [MEM-59] - Low endotoxin, Azide free
See all CD43 primary antibodies
DescriptionMouse monoclonal [MEM-59] to CD43 - Low endotoxin, Azide free
SpecificityThe antibody MEM-59 recognizes neuraminidase-sensitive epitope on CD43. The antibody activates T lymphocytes and also induces apoptosis in hemopoietic progenitor cells.
Tested applicationsSuitable for: IHC-P, Flow Cyt, IP, WB, Functional Studiesmore details
Species reactivityReacts with: Human
Human T lymphocytes
- Positive tissue: spleen, thymus, tonsil
General notesPreserved by filter sterilization
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: None
Constituents: PBS, pH 7.4
Concentration information loading...
Purity>95% by SDS-PAGE
- Anti-CD43 antibody [MEM-59], prediluted (Alexa Fluor® 488) (ab187599)
- Anti-CD43 antibody [MEM-59] (FITC) (ab21853)
- Anti-CD43 antibody [MEM-59] (Allophycocyanin/Cy7 ®) (ab233451)
- Anti-CD43 antibody [MEM-59] (Biotin) (ab28104)
- Anti-CD43 antibody [MEM-59] (Phycoerythrin) (ab60903)
- Anti-CD43 antibody [MEM-59] (ab9088)
Our Abpromise guarantee covers the use of ab46702 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 10 µg/ml.|
|Flow Cyt||Use a concentration of 1 µg/ml.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|IP||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration. Predicted molecular weight: 40 kDa.|
|Functional Studies||Use at an assay dependent concentration. The antibody activates T lymphocytes and also induces apoptosis in hemopoietic progenitor cells.|
FunctionOne of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
Tissue specificityCell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
modificationsGlycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
- Information by UniProt
- CD 43 antibody
- CD43 antibody
- CD43 antigen antibody
ab46702 has not yet been referenced specifically in any publications.