Product nameAnti-CD43 antibody [MT1]
See all CD43 primary antibodies
DescriptionMouse monoclonal [MT1] to CD43
Tested applicationsSuitable for: WB, IHC-P, IHC-Frmore details
Species reactivityReacts with: Human
- Human mantle cell lymphoma tissue.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.097% Sodium azide
Constituent: Tissue culture supernatant
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab89691 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Trypsin digestion of paraffin sections may enhance staining in some cases. 60 minutes primary antibody incubation at 25oC. Standard ABC technique.
IHC-Fr: 1/20 - 1/40.
WB: 1/250 - 1/400. Predicted molecular weight: 40 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionOne of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
Tissue specificityCell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
modificationsGlycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
- Information by UniProt
- CD 43 antibody
- CD43 antibody
- CD43 antigen antibody
This product has been referenced in:
- Guye P et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun 7:10243 (2016). IF ; Human . Read more (PubMed: 26732624) »
- Xiao LI et al. Multiple myeloma-associated skin light chain amyloidosis: A case of misdiagnosis. Oncol Lett 11:3617-3620 (2016). IHC ; Human . Read more (PubMed: 27284363) »