Product nameAnti-CD45RA antibody [HI100], prediluted (PE/Cy7 ®)
See all CD45RA primary antibodies
DescriptionMouse monoclonal [HI100] to CD45RA, prediluted (PE/Cy7 ®)
ConjugationPE/Cy7 ®. Ex: 496nm, Em: 774nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human
The details of the immunogen for this antibody are not available.
- Normal Human peripheral blood cells.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 99% PBS, 0.2% BSA
Concentration information loading...
PurityProtein G purified
Light chain typekappa
- Anti-CD45RA antibody [HI100], prediluted (PerCP/Cy5.5®) (ab155362)
- Anti-CD45RA antibody [HI100], prediluted (Allophycocyanin) (ab155384)
- Anti-CD45RA antibody [HI100] (FITC) (ab210268)
- Anti-CD45RA antibody [HI100] (Phycoerythrin) (ab210269)
- Anti-CD45RA antibody [HI100] (Allophycocyanin/Cy7 ®) (ab218643)
- Anti-CD45RA antibody [HI100] (ab218645)
- Anti-CD45RA antibody [HI100] (violetFluor™ 450) (ab218646)
- Anti-CD45RA antibody [HI100] (redFluor™ 710) (ab218648)
Our Abpromise guarantee covers the use of ab155383 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 5µl for 106 cells.
ab154458 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
FunctionProtein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Involvement in diseaseSevere combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive
Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 tyrosine-protein phosphatase domains.
DomainThe first PTPase domain interacts with SKAP1.
modificationsHeavily N- and O-glycosylated.
Cellular localizationMembrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
- Information by UniProt
- B220 antibody
- CD45 antibody
- CD45 antigen antibody
ab155383 has not yet been referenced specifically in any publications.