Product nameAnti-CD62E antibody [1.2B6]
See all CD62E primary antibodies
DescriptionMouse monoclonal [1.2B6] to CD62E
SpecificityThis antibody recognises the human CD62E and CD62P cell surface antigens binding to a common epitope on these members of the selectin family.
Tested applicationsSuitable for: ELISA, Flow Cyt, IHC-Fr, IP, WBmore details
Unsuitable for: IHC-P
Species reactivityReacts with: Human, Pig
Human E-Selectin (ELAM-1)
This antibody inhibits neutrophil adhesion to E-selectin and to P-selectin. E-selectin (ELAM-1) is expressed on the surface of activated endothelial cells.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Concentration information loading...
PurityProtein A purified
Purification notesPurified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Primary antibody notesThis antibody inhibits neutrophil adhesion to E-selectin and to P-selectin. E-selectin (ELAM-1) is expressed on the surface of activated endothelial cells.
Our Abpromise guarantee covers the use of ab6630 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.|
|Flow Cyt||Use a concentration of 10 µg/ml.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|IHC-Fr||Use a concentration of 1 - 10 µg/ml.|
|IP||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration. Non-reduced only.|
FunctionCell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
Sequence similaritiesBelongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains.
- Information by UniProt
- CD26E antibody
- CD62 antigen-like family member E antibody
- CD62E antibody
This product has been referenced in:
- Yuan X et al. Recipient treatment with acetylcholinesterase inhibitor donepezil attenuates primary graft failure in rats through inhibiting post-transplantational donor heart ischaemia/reperfusion injury. Eur J Cardiothorac Surg 53:400-408 (2018). Read more (PubMed: 28950359) »
- Zhang X et al. Long Noncoding RNA Malat1 Regulates Cerebrovascular Pathologies in Ischemic Stroke. J Neurosci 37:1797-1806 (2017). Read more (PubMed: 28093478) »