Overview

  • Product name

    Anti-CD62L antibody [EPR22188-297]
    See all CD62L primary antibodies
  • Description

    Rabbit monoclonal [EPR22188-297] to CD62L
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cytmore details
    Unsuitable for: ICC/IF,IHC-P or WB
  • Species reactivity

    Reacts with: Rat
  • Immunogen

    Recombinant full length protein within Rat CD62L aa 1 to the C-terminus. The exact sequence is proprietary.
    Database link: Q63762

  • Positive control

    • Flow Cyt: Rat primary splenocytes.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab218829 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/500.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or WB.
  • Target

    • Relevance

      CD62L is a cell surface component that is a member of a family of adhesion/homing receptors. These play important roles in leukocyte-endothelial cell interactions. CD62L is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.
    • Cellular localization

      Cell Membrane; single-pass type I membrane protein.
    • Database links

    • Alternative names

      • A.11 antibody
      • AI528707 antibody
      • CD62 antigen ligand antibody
      • CD62 antigen-like family member L antibody
      • CD62L antigen antibody
      • gp90 MEL antibody
      • hLHRc antibody
      • IgA nephropathy, susceptibility to, included antibody
      • L Selectin antibody
      • L selectin precursor antibody
      • LAM 1 antibody
      • LAM1 antibody
      • LECAM1 antibody
      • Leu 8 antibody
      • Leu8 antibody
      • Leukocyte adhesion molecule 1 antibody
      • Leukocyte endothelial cell adhesion molecule 1 antibody
      • Leukocyte surface antigen Leu 8 antibody
      • Leukocyte surface antigen Leu8 antibody
      • Leukocyte-endothelial cell adhesion molecule 1 antibody
      • LNHR antibody
      • LSEL antibody
      • Ly-22 antibody
      • Ly-m22 antibody
      • Lyam 1 antibody
      • LYAM1 antibody
      • Lymph node homing receptor antibody
      • Lymphocyte adhesion molecule 1 antibody
      • Lymphocyte antigen 22 antibody
      • Lymphocyte surface MEL-14 antigen antibody
      • PLNHR antibody
      • Selectin L antibody
      • Selectin L (lymphocyte adhesion molecule 1) antibody
      • Selectin, lymphocyte antibody
      • SELL antibody
      • TQ1 antibody
      see all

    Images

    • Flow cytometric analysis of rat primary splenocytes labeling CD62L with ab218829 at 1/500 dilution (top right panel), compared with a Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730) (Upper left). Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077) at 1/2000 dilution was used as the secondary antibody.

      Top panel: Cells were stained with Alexa Fluor® 647-conjugated CD3 and rabbit IgG (Left) or anti-CD62L RabMab (Right). Data shown was gated on viable cells.

      Down regulation of CD62L on activated T cells (CD3+FSChigh, blue) compared to Naïve T cells (CD3+CD62L+, red) was shown on the bottom panel.

    References

    ab218829 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab218829.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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