Key features and details
- Rat monoclonal [MEL-14] to CD62L (Biotin)
- Suitable for: Microcytotoxicity testing, Flow Cyt, IHC-Fr, IP, Blocking
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2a
Product nameAnti-CD62L antibody [MEL-14] (Biotin)
See all CD62L primary antibodies
DescriptionRat monoclonal [MEL-14] to CD62L (Biotin)
Tested applicationsSuitable for: Microcytotoxicity testing, Flow Cyt, IHC-Fr, IP, Blockingmore details
Species reactivityReacts with: Mouse
Tissue/ cell preparation of C3H/eb cloned B lymphoma 38C-13 (Mouse)
The monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.14% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride
Concentration information loading...
Primary antibody notesThe monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling.
Light chain typekappa
- Anti-CD62L antibody [MEL-14] (ab119834)
- Anti-CD62L antibody [MEL-14] - Low endotoxin, Azide free (ab174597)
- Anti-CD62L antibody [MEL-14] (redFluor™ 710) (ab242077)
- Anti-CD62L antibody [MEL-14] (FITC) (ab24876)
- Anti-CD62L antibody [MEL-14] (PE/Cy7®) (ab25569)
- Anti-CD62L antibody [MEL-14] (APC) (ab41459)
Our Abpromise guarantee covers the use of ab24969 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Microcytotoxicity testing||Use at an assay dependent concentration.|
|Flow Cyt||Use at an assay dependent concentration.
ab18445 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
|IHC-Fr||Use at an assay dependent concentration.|
|IP||Use at an assay dependent concentration.|
|Blocking||Use at an assay dependent concentration.
In vivo and in vitro blocking of adhesion.
FunctionCell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
Tissue specificityExpressed in B cell lines and T lymphocytes.
Sequence similaritiesBelongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 2 Sushi (CCP/SCR) domains.
- Information by UniProt
- A.11 antibody
- AI528707 antibody
- CD62 antigen ligand antibody
ab24969 has not yet been referenced specifically in any publications.