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Mouse monoclonal [GM-2H6] to CD66b
This antibody exclusively recognizes CD66b (CEACAM8).
Competitive ELISA more details
The complete extracellular region of human CD66b (CEACAM8) cDNA.
Shipped at 4°C. Store at +4°C.
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Protein G purified
The antibody was purified from cell culture supernatants.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
cELISA: Use at an assay dependent dilution.
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Information by UniProt
Carcinoembryonic antigen CGM6 antibody
Carcinoembryonic antigen gene family member 6 antibody
Carcinoembryonic antigen related cell adhesion molecule 8 antibody
Flow Cytometry - Anti-CD66b antibody [GM-2H6] (ab48589)
Ab48589, staining CD66b (CEACAM8) by Flow Cytometry.
BOSC23 cells were transiently transfected with expression vectors containing either the cDNA of CEACAM1, CEACAM3-8 or PSG. The latter was expressed as a membrane bound fusion protein. Expression of the constructs was tested with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6: D14HD11; CEACAM7: BAC2; CEACAM8: Tet2; PSG: BAP3; green curves). An irrelevant monoclonal antibody served as a negative control (black curves). For specificity testing, ab48589 was tested on all CEACAM transfectants. A positive signal was obtained only with CEACAM8 (CD66b) transfected cells (red curve).
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