Overview

  • Product name

    Anti-CD6/T12 antibody [3F7B5]
    See all CD6/T12 primary antibodies
  • Description

    Mouse monoclonal [3F7B5] to CD6/T12
  • Host species

    Mouse
  • Tested applications

    Suitable for: Flow Cyt, ICC/IF, WB, IHC-Fr, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human CD6/T12. Human rheumatoid synovial T cell line ST-1
    Database link: P30203

  • Positive control

    • CCRF-CEM, Jurkat cells, Tonsil tissue.
  • General notes

    Previously labelled as CD6. 

Properties

Applications

Our Abpromise guarantee covers the use of ab193341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.5-1µg for 106 cells.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

ICC/IF Use a concentration of 0.5 - 1 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 90-130 kDa (predicted molecular weight: 72 kDa).
IHC-Fr Use a concentration of 0.5 - 1 µg/ml.
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Involved in cell adhesion. Binds to CD166.
  • Tissue specificity

    Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
  • Sequence similarities

    Contains 3 SRCR domains.
  • Post-translational
    modifications

    After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
    Contains intrachain disulfide bond(s).
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD_antigen=CD6 antibody
    • CD6 antibody
    • CD6 antigen Tp120 antibody
    • CD6 molecule antibody
    • CD6_HUMAN antibody
    • FLJ44171 antibody
    • OX52 antibody
    • T cell differentiation antigen CD6 antibody
    • T-cell differentiation antigen CD6 antibody
    • T12 antibody
    • TP120 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed paraffin embedded human tonsil labeling CD6/T12 with ab193341 at 0.5 μg/mL.

  • Immunohistochemical analysis of formalin fixed paraffin embedded human tonsil labeling CD6/T12 with ab193341 at 0.5 μg/mL.

References

ab193341 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab193341.
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