Overview

  • Product name

  • Description

    Rabbit polyclonal to CD6/T12
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment (His-T7-tag) corresponding to Mouse CD6/T12 aa 30-204. Expressed in E.coli. N-terminal tags.
    Sequence:

    MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- G TIPNMTLDLE ERLGIRLVNG SSRCSGSVKV LLESWEPVCAAHWNRAATEAVCKALNCGDS GKVTYLMPPT SELPPGATSG NTSSAGNTTW ARAPTERCRG ANWQFCKVQD QECSSDRRLV WVTCAENQAV RLVDGSSRCAGRVEMLEHGE WGTVCDDTWDLQDAHVVCKQ LKCG


    Database link: Q61003

  • Positive control

    • IHC-P: Mouse spleen tissue. WB: Jurkat whole cell lysate (ab7899); Mouse lymph node lysate; Recombinant mouse CD6/T12 protein.
  • General notes

    Previously labelled as CD6. 

Properties

Applications

Our Abpromise guarantee covers the use of ab231314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 72 kDa.
IHC-P Use a concentration of 5 - 20 µg/ml.

Target

  • Function

    Involved in cell adhesion. Binds to CD166.
  • Tissue specificity

    Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
  • Sequence similarities

    Contains 3 SRCR domains.
  • Post-translational
    modifications

    After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
    Contains intrachain disulfide bond(s).
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD_antigen=CD6 antibody
    • CD6 antibody
    • CD6 antigen Tp120 antibody
    • CD6 molecule antibody
    • CD6_HUMAN antibody
    • FLJ44171 antibody
    • OX52 antibody
    • T cell differentiation antigen CD6 antibody
    • T-cell differentiation antigen CD6 antibody
    • T12 antibody
    • TP120 antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded mouse spleen tissue stained for CD6/T12 using ab231314 at 20 µg/ml in immunohistochemical analysis. DAB staining.

  • Anti-CD6/T12 antibody (ab231314) at 2 µg/ml + Jurkat (human T cell leukemia cell line from peripheral blood) cell lysate

    Predicted band size: 72 kDa

  • Anti-CD6/T12 antibody (ab231314) at 2 µg/ml + Mouse lymph node lysate

    Predicted band size: 72 kDa

  • Anti-CD6/T12 antibody (ab231314) at 2 µg/ml + Recombinant mouse CD6/T12 protein

    Predicted band size: 72 kDa

References

ab231314 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab231314.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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