Overview

  • Product name

    Anti-CD6/T12 antibody [MAE-1C10] (PerCP)
    See all CD6/T12 primary antibodies
  • Description

    Mouse monoclonal [MAE-1C10] to CD6/T12 (PerCP)
  • Host species

    Mouse
  • Conjugation

    PerCP. Ex: 482nm, Em: 675nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human CD6/T12.

  • Positive control

    • EDTA-anticoagulated normal peripheral blood. The antigen is found on >80% normal mature T cells and a sub-population of B cells in peripheral blood. CD6/T12 also exhibits weak expression on cortical thymocytes and the majority of chronic B lymphocytic leukaemias.
  • General notes

    Previously labelled as CD6. 

Properties

Applications

Our Abpromise guarantee covers the use of ab90898 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 20µl for 106 cells.

ab118658 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    Involved in cell adhesion. Binds to CD166.
  • Tissue specificity

    Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
  • Sequence similarities

    Contains 3 SRCR domains.
  • Post-translational
    modifications

    After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
    Contains intrachain disulfide bond(s).
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD_antigen=CD6 antibody
    • CD6 antibody
    • CD6 antigen Tp120 antibody
    • CD6 molecule antibody
    • CD6_HUMAN antibody
    • FLJ44171 antibody
    • OX52 antibody
    • T cell differentiation antigen CD6 antibody
    • T-cell differentiation antigen CD6 antibody
    • T12 antibody
    • TP120 antibody
    see all

Images

  • Flow cytometry analysis of CD6/T12 in normal peripheral blood from a Human donor using ab90898 at 20 µl/106 cells. The encircled cells are CD6/T12+ (T cells and a subset of B cells).

References

ab90898 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab90898.
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