Overview

  • Product name
    Anti-CD70 antibody [FR70] - Low endotoxin, Azide free
    See all CD70 primary antibodies
  • Description
    Rat monoclonal [FR70] to CD70 - Low endotoxin, Azide free
  • Host species
    Rat
  • Tested applications
    Suitable for: Flow Cyt, Functional Studiesmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • 4-day LPS activated BALB/c splenocytes
  • General notes

    Endotoxin Level: Less than 0.001 ng/ug antibody, as determined by the LAL assay.

Properties

Applications

Our Abpromise guarantee covers the use of ab171218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.5µg for 105-8 cells.

A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 µL.

ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Functional Studies Use at an assay dependent concentration.

Target

  • Function
    Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
  • Sequence similarities
    Belongs to the tumor necrosis factor family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 27L antibody
    • CD 70 antibody
    • CD27 L antibody
    • CD27 LG antibody
    • CD27 ligand antibody
    • CD27-L antibody
    • CD27L antibody
    • CD27LG antibody
    • CD70 antibody
    • CD70 antigen antibody
    • CD70 molecule antibody
    • CD70_HUMAN antibody
    • Ki 24 antigen antibody
    • Ki24 antigen antibody
    • Surface antigen CD70 antibody
    • TNFSF 7 antibody
    • TNFSF7 antibody
    • Tumor necrosis factor (ligand) superfamily, member 7 antibody
    • Tumor necrosis factor ligand superfamily member 7 antibody
    see all

Images

  • Flow cytometric analysis of 4-day LPS activated BALB/c splenocytes labeling CD70 with 0.25 µg ab171218 (filled histogram) with Rat IgG2b kappa Isotype Control (open histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE. Total viable cells were used for analysis.

References

ab171218 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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