Key features and details
- Rat monoclonal [TAN 1-7] to CD70
- Suitable for: ELISA, Flow Cyt, ICC/IF
- Reacts with: Mouse
- Isotype: IgG2a
Product nameAnti-CD70 antibody [TAN 1-7]
See all CD70 primary antibodies
DescriptionRat monoclonal [TAN 1-7] to CD70
SpecificityThis antibody is a non-depleting mAb that blocks the CD70-CD27 interaction.
Tested applicationsSuitable for: ELISA, Flow Cyt, ICC/IFmore details
Species reactivityReacts with: Mouse
Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
- Activated dendritic cells.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein A/G purified
Clone numberTAN 1-7
Our Abpromise guarantee covers the use of ab108482 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.|
|Flow Cyt||Use at an assay dependent concentration.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
|ICC/IF||Use at an assay dependent concentration.|
FunctionCytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Sequence similaritiesBelongs to the tumor necrosis factor family.
- Information by UniProt
- CD 27L antibody
- CD 70 antibody
- CD27 L antibody
ab108482 has been referenced in 2 publications.
- Taraban VY et al. Invariant NKT cells promote CD8+ cytotoxic T cell responses by inducing CD70 expression on dendritic cells. J Immunol 180:4615-20 (2008). PubMed: 18354184
- Rowley TF & Al-Shamkhani A Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo. J Immunol 172:6039-46 (2004). PubMed: 15128787