Anti-CD80 antibody [16-10A1] (ab106162)
Key features and details
- Armenian hamster monoclonal [16-10A1] to CD80
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Isotype: IgG
Related conjugates and formulations
Overview
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Product name
Anti-CD80 antibody [16-10A1]
See all CD80 primary antibodies -
Description
Armenian hamster monoclonal [16-10A1] to CD80 -
Host species
Armenian hamster -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to Mouse CD80. CD80-transfected CHO cell line.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.87% Monobasic dihydrogen sodium phosphate, 0.14% Sodium chloride -
Concentration information loading...
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Purity
SDS-PAGE -
Clonality
Monoclonal -
Clone number
16-10A1 -
Isotype
IgG -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Conjugation kits
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106162 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use at an assay dependent concentration.
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Notes |
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Flow Cyt
Use at an assay dependent concentration. |
Target
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Function
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. -
Tissue specificity
Expressed on activated B-cells, macrophages and dendritic cells. -
Sequence similarities
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 12519 Mouse
- SwissProt: Q00609 Mouse
- Unigene: 89474 Mouse
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Alternative names
- Activation B7-1 antigen antibody
- B lymphocyte activation antigen B7 antibody
- B7 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (7)
ab106162 has been referenced in 7 publications.
- Qian J et al. Mechanism of TGF-ß1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis. Exp Ther Med 20:1541-1549 (2020). PubMed: 32742385
- Mukherjee S et al. Modulation of cell cycle progression by CTLA4-CD80/CD86 interactions on CD4+ T cells depends on strength of the CD3 signal: critical role for IL-2. J Leukoc Biol 80:66-74 (2006). PubMed: 16624934
- Odobasic D et al. Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis. J Am Soc Nephrol 16:2012-22 (2005). PubMed: 15944341
- Reiser J et al. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest 113:1390-7 (2004). PubMed: 15146236
- Gueirard P et al. Bordetella bronchiseptica persists in the nasal cavities of mice and triggers early delivery of dendritic cells in the lymph nodes draining the lower and upper respiratory tract. Infect Immun 71:4137-43 (2003). PubMed: 12819105
- Mencacci A et al. CD80+Gr-1+ myeloid cells inhibit development of antifungal Th1 immunity in mice with candidiasis. J Immunol 169:3180-90 (2002). PubMed: 12218136
- Horspool JH et al. Nucleic acid vaccine-induced immune responses require CD28 costimulation and are regulated by CTLA4. J Immunol 160:2706-14 (1998). PubMed: 9510170