Overview

  • Product name
    Anti-CD80 antibody [MEM-233]
    See all CD80 primary antibodies
  • Description
    Mouse monoclonal [MEM-233] to CD80
  • Host species
    Mouse
  • Specificity
    CD80 antigen
  • Tested applications
    Suitable for: Flow Cyt, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Fusion protein (Human).

  • General notes

    This product was changed from ascites to tissue culture supernatant on 24th January 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab8239 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use a concentration of 1 - 10 µg/ml.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 
IP Use at an assay dependent concentration.

Target

  • Function
    Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
  • Tissue specificity
    Expressed on activated B-cells, macrophages and dendritic cells.
  • Sequence similarities
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • Activation B7-1 antigen antibody
      • B lymphocyte activation antigen B7 antibody
      • B7 antibody
      • B7-1 antibody
      • B7-1 antigen antibody
      • B7.1 antibody
      • BB1 antibody
      • CD28 antigen ligand 1 antibody
      • CD28LG antibody
      • CD28LG1 antibody
      • CD80 antibody
      • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody
      • CD80 antigen antibody
      • CD80 molecule antibody
      • CD80_HUMAN antibody
      • Costimulatory factor CD80 antibody
      • costimulatory molecule variant IgV-CD80 antibody
      • CTLA-4 counter-receptor B7.1 antibody
      • LAB7 antibody
      • T-lymphocyte activation antigen CD80 antibody
      see all

    References

    This product has been referenced in:
    • Reiner A  et al. Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189. Int J Mol Sci 16:758-87 (2014). Read more (PubMed: 25561230) »

    See 1 Publication for this product

    Publishing research using ab8239? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    4 reviews or Q&A

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    Votes: Highest First

    Do you have any information on whether ab8239 reacts with any other B7 family molecules, besides CD80?

    Thank you for your enquiry. We regret to inform you that we do not have more information.

    is this antibody working in anti-rat immunhistochemistry?

    This antibody has not been tested IHC on rat tissue, therefore we cannot guarantee results.

    Have you an image of a membrane/Western blot that was revealed with this antibody and shows the profile of migration of CD80 ?

    We have no western blot images available for this antibody. However, if the antibody does not perform as stated on the datasheet, Abcam will offer a full refund or a replacement.

    Does this antibody cross react with the dog.

    This antibody has not yet been tested on dog

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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