Anti-CD80 antibody [MEM-233] (ab8239)
- Datasheet
- References (2)
- Protocols
Overview
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Product name
Anti-CD80 antibody [MEM-233]
See all CD80 primary antibodies -
Description
Mouse monoclonal [MEM-233] to CD80 -
Host species
Mouse -
Specificity
CD80 antigen -
Tested applications
Suitable for: Flow Cyt, IPmore details -
Species reactivity
Reacts with: Human -
Immunogen
Fusion protein (Human).
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General notes
This product was changed from ascites to tissue culture supernatant on 24th January 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Protein A purified -
Purification notes
Purified from TCS. Purity >95% by SDS-PAGE. -
Clonality
Monoclonal -
Clone number
MEM-233 -
Isotype
IgG1 -
Light chain type
unknown -
Research areas
Associated products
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Alternative Versions
- Anti-CD80 antibody [MEM-233] (FITC) (ab18279)
- Anti-CD80 antibody [MEM-233] (PE/Cy5®) (ab233572)
- Anti-CD80 antibody [MEM-233] (PE/Cy7 ®) (ab234229)
- Anti-CD80 antibody [MEM-233] (Alexa Fluor® 700) (ab270668)
- Anti-CD80 antibody [MEM-233] (Allophycocyanin) (ab27554)
- Anti-CD80 antibody [MEM-233], prediluted (Phycoerythrin) (ab69778)
- Anti-CD80 antibody [MEM-233] (PerCP) (ab82410)
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab8239 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use a concentration of 1 - 10 µg/ml. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
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| IP | Use at an assay dependent concentration. |
Target
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Function
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. -
Tissue specificity
Expressed on activated B-cells, macrophages and dendritic cells. -
Sequence similarities
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 941 Human
- Omim: 112203 Human
- SwissProt: P33681 Human
- Unigene: 838 Human
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Alternative names
- Activation B7-1 antigen antibody
- B lymphocyte activation antigen B7 antibody
- B7 antibody
see all
References
This product has been referenced in:
- Reiner A et al. Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189. Int J Mol Sci 16:758-87 (2014). Read more (PubMed: 25561230) »
- Hoffmann D et al. Evaluation of twenty-one human adenovirus types and one infectivity-enhanced adenovirus for the treatment of malignant melanoma. J Invest Dermatol 128:988-98 (2008). Read more (PubMed: 17960177) »
