Anti-CD80 antibody [MEM-233] (ab8239)
- Datasheet
- References (2)
- Protocols
Overview
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Product nameAnti-CD80 antibody [MEM-233]
See all CD80 primary antibodies -
DescriptionMouse monoclonal [MEM-233] to CD80
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Host speciesMouse
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SpecificityCD80 antigen
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Tested applicationsSuitable for: Flow Cyt, IPmore details
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Species reactivityReacts with: Human
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Immunogen
Fusion protein (Human).
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General notes
This product was changed from ascites to tissue culture supernatant on 24th January 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity>95% by SDS-PAGE
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Purification notesPurified from TCS
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ClonalityMonoclonal
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Clone numberMEM-233
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IsotypeIgG1
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Light chain typeunknown
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Research areas
Associated products
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Alternative Versions
- Anti-CD80 antibody [MEM-233] (FITC) (ab18279)
- Anti-CD80 antibody [MEM-233] (PE/Cy5®) (ab233572)
- Anti-CD80 antibody [MEM-233] (PE/Cy7 ®) (ab234229)
- Anti-CD80 antibody [MEM-233] (Allophycocyanin) (ab27554)
- Anti-CD80 antibody [MEM-233], prediluted (Phycoerythrin) (ab69778)
- Anti-CD80 antibody [MEM-233] (PerCP) (ab82410)
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab8239 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use a concentration of 1 - 10 µg/ml. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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| IP | Use at an assay dependent concentration. |
Target
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FunctionInvolved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
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Tissue specificityExpressed on activated B-cells, macrophages and dendritic cells.
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Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localizationMembrane.
- Information by UniProt
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Database links
- Entrez Gene: 941 Human
- Omim: 112203 Human
- SwissProt: P33681 Human
- Unigene: 838 Human
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Alternative names
- Activation B7-1 antigen antibody
- B lymphocyte activation antigen B7 antibody
- B7 antibody
see all
References
This product has been referenced in:
- Reiner A et al. Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189. Int J Mol Sci 16:758-87 (2014). Read more (PubMed: 25561230) »
- Hoffmann D et al. Evaluation of twenty-one human adenovirus types and one infectivity-enhanced adenovirus for the treatment of malignant melanoma. J Invest Dermatol 128:988-98 (2008). Read more (PubMed: 17960177) »
