Product nameCD81 Exosome Capture Beads
See all Exosome kits
Sample typeCell culture supernatant, Urine, Plasma
Species reactivityReacts with: Human
CD81 Exosome Capture Beads (ab239687) consists of a simple bead population, coated with a capture antibody (CD81) for isolation/detection of exosome.
The beads are intended for the immunoisolation (immunomagnetic or FACS) and Flow Cytometry analysis of pre-enriched CD81+
human exosomes from biofluids (plasma, urine) or cell culture media.
Storage instructionsStore at +4°C. Please refer to protocols.
Components 25 tests CD81+ [MEM-38] capture beads 1 x 2500µl
RelevanceExosomes are best defined as extracellular vesicles that are released from cells upon fusion of an intermediate endocytic compartment, the multivesicular body (MVB), with the plasma membrane. This liberates intraluminal vesicles (ILVs) into the extracellular milieu and the vesicles thereby released are what we know as exosomes. They contain abundant proteins, DNA, mRNA, and non-coding RNAs. They are now considered as an additional mechanism for intercellular communication, allowing cells to exchange proteins, lipids and genetic material. Increasing studies have shown that exosomes play an important role in tumour initiation, growth, progression, metastasis, drug resistance and immune escape.
ab239687 has not yet been referenced specifically in any publications.