Anti-CD89 antibody [A59] (ab234188)

Submit a review Submit a question

Key features and details

  • Mouse monoclonal [A59] to CD89
  • Suitable for: Flow Cyt
  • Reacts with: Human
  • Isotype: IgG1

Overview

  • Product name

    Anti-CD89 antibody [A59]
    See all CD89 primary antibodies

  • Description

    Mouse monoclonal [A59] to CD89

  • Host species

    Mouse

  • Tested applications

    Suitable for: Flow Cytmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Non human primates

  • Immunogen

    Tissue, cells or virus corresponding to Human CD89. (Ag8.653 myeloma cells).

  • Positive control

    • Flow Cytometry: Human peripheral blood.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.40
    Preservative: 0.0975% Sodium azide
    Constituent: PBS
  • Concentration information loading...

  • Purity

    Protein A purified

  • Purification notes

    Purity > 95% (by SDS-PAGE).

  • Clonality

    Monoclonal

  • Clone number

    A59

  • Isotype

    IgG1

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab234188 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • Function

    Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.

  • Tissue specificity

    Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.

  • Sequence similarities

    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • CD89 antibody
      • Fc alpha receptor antibody
      • Fc fragment of IgA, receptor for antibody
      • FCAR antibody
      • FCAR_HUMAN antibody
      • IgA Fc receptor antibody
      • Immunoglobulin alpha Fc receptor antibody
      see all

    Images

    • Flow Cytometry - Anti-CD89 antibody [A59] (ab234188)
      Flow Cytometry - Anti-CD89 antibody [A59] (ab234188)

      Flow cytometric analysis of human peripheral blood labeling CD89 with ab234188. Surface staining. Gated for leukocytes.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab234188? Please let us know so that we can cite the reference in this datasheet.

    ab234188 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab234188.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com