Overview

  • Product name

    Anti-CD89 antibody [A59] (FITC)
    See all CD89 primary antibodies
  • Description

    Mouse monoclonal [A59] to CD89 (FITC)
  • Host species

    Mouse
  • Conjugation

    FITC. Ex: 493nm, Em: 528nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Non human primates
  • Immunogen

    Tissue, cells or virus corresponding to Human CD89. (Ag8.653 myeloma cells).

  • Positive control

    • Flow Cyt: Human peripheral blood.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Store In the Dark.
  • Storage buffer

    Preservative: 0.0975% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Size exclusion
  • Purification notes

    Purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
  • Clonality

    Monoclonal
  • Clone number

    A59
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab239245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 4µl for 106 cells.

(or 100 µl of whole blood).

Target

  • Function

    Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
  • Tissue specificity

    Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
  • Sequence similarities

    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD89 antibody
    • Fc alpha receptor antibody
    • Fc fragment of IgA, receptor for antibody
    • FCAR antibody
    • FCAR_HUMAN antibody
    • IgA Fc receptor antibody
    • Immunoglobulin alpha Fc receptor antibody
    see all

Images

  • Flow cytometric analysis of human peripheral blood labeling CD89 with ab239245. Surface staining. Gated on leukocytes.

References

ab239245 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab239245.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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