Overview

  • Product name

  • Description

    Rabbit Polyclonal to CD89
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Fusion protein within Human CD89 (internal sequence). The exact sequence is proprietary. Fusion protein corresponding to a region derived from internal residues of human CD89. The identity of the protein fusion partner is GST.
    Database link: P24071

  • Positive control

    • Mouse brain tissue lysate; Human thyroid cancer tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab197936 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/100.
WB 1/200 - 1/1000. Predicted molecular weight: 32 kDa.

Target

  • Function

    Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
  • Tissue specificity

    Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
  • Sequence similarities

    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD89 antibody
    • Fc alpha receptor antibody
    • Fc fragment of IgA, receptor for antibody
    • FCAR antibody
    • FCAR_HUMAN antibody
    • IgA Fc receptor antibody
    • Immunoglobulin alpha Fc receptor antibody
    see all

Images

  • Anti-CD89 antibody (ab197936) at 1/700 dilution + Mouse brain tissue lysate at 40 µg

    Predicted band size: 32 kDa


    Exposure time: 10 seconds
  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling CD89 with ab197936 at 1/20.

References

ab197936 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab197936.
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