Key features and details
- Rat monoclonal [G7] to CD90 / Thy1 (PE/Cy5®)
- Suitable for: Cellular Activation, Functional Studies, Flow Cyt, IHC-Fr
- Reacts with: Mouse
- Conjugation: PE/Cy5®. Ex: 496nm, Em: 670nm
- Isotype: IgG2c
Product nameAnti-CD90 / Thy1 antibody [G7] (PE/Cy5®)
See all CD90 / Thy1 primary antibodies
DescriptionRat monoclonal [G7] to CD90 / Thy1 (PE/Cy5®)
ConjugationPE/Cy5®. Ex: 496nm, Em: 670nm
Specificityab25272 is specific for Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A).
Tested applicationsSuitable for: Cellular Activation, Functional Studies, Flow Cyt, IHC-Frmore details
Species reactivityReacts with: Mouse
The details of the immunogen for this antibody are not available.
General notesThis product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.
ab25272 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. ab25272 has also been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: PBS, 0.2% Gelatin, 16% Sucrose
Concentration information loading...
Primary antibody notesab25272 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. ab25272 has also been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma.
Light chain typekappa
Our Abpromise guarantee covers the use of ab25272 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Cellular Activation||Use at an assay dependent concentration.
In vitro T cells activation: Use at an assay dependent dilution
|Functional Studies||Use at an assay dependent concentration.
Induction of apoptosis: Use at as assay dependent dilution
|Flow Cyt||Use 0.2µg for 106 cells.|
|IHC-Fr||Use at an assay dependent concentration.
Use at an assay dependent dilution
FunctionMay play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Sequence similaritiesContains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular localizationCell membrane.
- Information by UniProt
- CD7 antibody
- CD90 antibody
- CD90 antigen antibody
ab25272 has been referenced in 7 publications.
- Hu J et al. Effects of menstrual blood-derived stem cells on endometrial injury repair. Mol Med Rep 19:813-820 (2019). PubMed: 30569163
- Hueber AO et al. Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism. J Exp Med 179:785-96 (1994). PubMed: 7906706
- Ucker DS et al. Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death. J Immunol 149:1583-92 (1992). PubMed: 1380534
- He HT et al. Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a Ca2(+)-independent mechanism. J Exp Med 173:515-8 (1991). PubMed: 1671083
- Sugiyama E et al. Selection of T cell receptor expression mutants through the functionally linked Ly-6A. Cell Immunol 130:271-80 (1990). PubMed: 1976441
- Tentori L et al. Proliferation and production of IL-2 and B cell stimulatory factor 1/IL-4 in early fetal thymocytes by activation through Thy-1 and CD3. J Immunol 140:1089-94 (1988). PubMed: 2893823
- Gunter KC et al. T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med 159:716-30 (1984). PubMed: 6142077