Key features and details
- Potent, selective lipoxygenase inhibitor
- CAS Number: 132465-11-3
- Purity: > 98%
- Soluble in DMSO to 10 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Product nameCDC, lipoxygenase inhibitor
DescriptionPotent, selective lipoxygenase inhibitor
Biological descriptionPotent, selective 12-Lipoxygenase (12-LO) inhibitor (IC50 = 63 nM). Also inhibits 15-LO and 5-LO (IC50 values are 3.33 and 1.89 μM respectively). Active in vivo.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 10 mM and in ethanol to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141560 has been referenced in 1 publication.
- Körner A et al. Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A. Nat Commun 10:633 (2019). PubMed: 30733433