Cdc25C peptide (ab204870)
Key features and details
- Purity: > 95% HPLC
- Suitable for: Functional Studies, HPLC
Description
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Product name
Cdc25C peptide
See all Cdc25C proteins and peptides -
Purity
> 95 % HPLC. -
Animal free
No -
Nature
Synthetic -
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Sequence
CKKLGEDQAEEISDDLLEDSLSDEDE
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Associated products
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Recombinant Protein
Specifications
Our Abpromise guarantee covers the use of ab204870 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
HPLC
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Form
Liquid -
Additional notes
ab204870 (Cdc25C peptide) can be utilized as a substrate for the active protein kinase ab105126 (Active human GRK1 full length protein)
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
pH: 7.5
See comments
General Info
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Alternative names
- CDC 25
- Cdc 25C
- CDC25
see all -
Function
Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDK1 and activate its kinase activity. -
Sequence similarities
Belongs to the MPI phosphatase family.
Contains 1 rhodanese domain. -
Developmental stage
Expressed predominantly in G2 phase. -
Post-translational
modificationsPhosphorylated by CHK1 on Ser-216. This phosphorylation creates a binding site for 14-3-3 protein and inhibits the phosphatase. Phosphorylated by PLK4. -
Cellular localization
Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab204870 has not yet been referenced specifically in any publications.