Overview

  • Product name

  • Description

    Rabbit polyclonal to Cdc37
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human Cdc37.
    Database link: Q16543

  • Positive control

    • WB: HeLa cell lysate. ICC/IF: Heat shocked HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab223361 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/200.
WB 1/2000. Predicted molecular weight: 44.5 kDa.

Target

  • Function

    Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
  • Sequence similarities

    Belongs to the CDC37 family.
  • Post-translational
    modifications

    Constitutively sumoylated by UBE2I.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • CDC 37 antibody
    • Cdc37 antibody
    • CDC37 cell division cycle 37 homolog antibody
    • CDC37 cell division cycle 37 S cerevisiae homolog antibody
    • CDC37 cell division cycle 37, S cerevisiae, homolog of antibody
    • Cdc37 homolog antibody
    • CDC37 protein antibody
    • CDC37_HUMAN antibody
    • CDC37A antibody
    • cell division cycle 37 antibody
    • Cell division cycle 37 homolog antibody
    • Hsp90 chaperone protein kinase targeting subunit antibody
    • Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody
    • Hsp90 chaperone protein kinase-targeting subunit antibody
    • Hsp90 co chaperone Cdc37 antibody
    • Hsp90 co-chaperone Cdc37 antibody
    • p50 antibody
    • p50Cdc37 antibody
    • S cerevisiae hypothetical protein CDC37 antibody
    see all

Images

  • Formaldehyde-fixed heat shocked HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for Cdc37 (yellow) using ab223361 at 1/200 dilution in ICC/IF. Secondary antibody: R-PE Goat Anti-Rabbit (yellow) at 1/200. The nuclear counter stain is DAPI (blue). The right-hand panel shows the merged images.

  • Anti-Cdc37 antibody (ab223361) at 1/2000 dilution + HeLa (human epithelial cell line from cervix adenocarcinoma) cell lysate

    Developed using the ECL technique.

    Predicted band size: 44.5 kDa

  • 2% Formaldehyde-fixed heat shocked HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for Cdc37 (green) using ab223361 at 1/200 dilution in ICC/IF. Secondary antibody: FITC Goat Anti-Rabbit at 1/200. The nuclear counter stain is DAPI (blue). The right-hand panel shows the merged images.

References

ab223361 has not yet been referenced specifically in any publications.

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