Product nameAnti-CDC42 binding protein kinase alpha antibody
See all CDC42 binding protein kinase alpha primary antibodies
DescriptionRabbit polyclonal to CDC42 binding protein kinase alpha
Specificityab196813 detects endogenous levels of total CDC42 binding protein kinase alpha protein.
Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human CDC42 binding protein kinase alpha (internal sequence).
Database link: Q5VT25
- Jurkat and COLO205 cell extracts.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS, 0.87% Sodium chloride
PBS (without Mg2+and Ca2+)
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab196813 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Our Abpromise guarantee covers the use of ab196813 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|ICC/IF||Use at an assay dependent concentration.|
|WB||1/500 - 1/3000. Predicted molecular weight: 197 kDa.|
FunctionMay act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
Tissue specificityAbundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.
Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 CNH domain.
Contains 1 CRIB domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 protein kinase domain.
Cellular localizationCytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
- Information by UniProt
- A930014J19Rik antibody
- CDC42 binding protein kinase alpha (DMPK like) antibody
- CDC42 binding protein kinase alpha antibody
ab196813 has not yet been referenced specifically in any publications.