Overview

  • Product name

    Anti-CDCA3 antibody - C-terminal
    See all CDCA3 primary antibodies
  • Description

    Rabbit polyclonal to CDCA3 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide derived from the C terminus of Human CDCA3.

  • Positive control

    • Human placenta tissue; HepG2 cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab167037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 29 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Relevance

    CDCA3 (Cell division cycle associated 3) is an F-box-like protein which is required for entry into mitosis. It is associated with SKP1 as part of a SCF (SKP1-cullin-F-box) protein ligase complex, and is required for the ubiquitination and degradation of the CDK1 inhibitory tyrosine kinase WEE1 at G2/M phase.
  • Cellular localization

    Cytoplasmic. Cytosol.
  • Database links

  • Alternative names

    • C8 antibody
    • CDCA 3 antibody
    • Cell division cycle associated 3 antibody
    • Cell division cycle associated protein 3 antibody
    • Gene rich cluster C8 antibody
    • Gene rich cluster protein C8 antibody
    • GRCC 8 antibody
    • GRCC8 antibody
    • MGC2577 antibody
    • TOME 1 antibody
    • TOME1 antibody
    • Trigger of mitotic entry 1 antibody
    • Trigger of mitotic entry protein 1 antibody
    see all

Images

  • All lanes : Anti-CDCA3 antibody - C-terminal (ab167037) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : HepG2 cell extract with immunizing peptide

    Predicted band size: 29 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue labeling CDCA3 with ab167037 at 5 µg/ml.

References

This product has been referenced in:

  • Zhang Y  et al. CDCA3 is a potential prognostic marker that promotes cell proliferation in gastric cancer. Oncol Rep 41:2471-2481 (2019). Read more (PubMed: 30816466) »
  • Qian W  et al. CDCA3 mediates p21-dependent proliferation by regulating E2F1 expression in colorectal cancer. Int J Oncol 53:2021-2033 (2018). Read more (PubMed: 30226575) »
See all 2 Publications for this product

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