Validated using a knockout cell line

Recombinant Anti-Cdk4 antibody [EPR4513-32-7] (ab108357)

Knockout Tested Rabbit recombinant monoclonal Cdk4 antibody [EPR4513-32-7]. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Human. Cited in 18 publication(s). Independently reviewed in 1 review(s).

Publishing research using ab108357? Please let us know so that we can cite the reference in this datasheet.

ab108357 has been referenced in 20 publications.

  • Fang G  et al. LncRNA MRAK048635_P1 is critical for vascular smooth muscle cell function and phenotypic switching in essential hypertension. Biosci Rep 39:N/A (2019). PubMed: 30833363
  • Shao G  et al. lncRNA CASC9 positively regulates CHK1 to promote breast cancer cell proliferation and survival through sponging the miR-195/497 cluster. Int J Oncol 54:1665-1675 (2019). PubMed: 30816435
  • Lang B & Zhao S miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2. Oncol Rep 39:71-80 (2018). PubMed: 29115564
  • Wang Y & Kong D LncRNA GAS5 Represses Osteosarcoma Cells Growth and Metastasis via Sponging MiR-203a. Cell Physiol Biochem 45:844-855 (2018). PubMed: 29414815
  • Rust A  et al. Burkholderia Lethal Factor 1, a Novel Anti-Cancer Toxin, Demonstrates Selective Cytotoxicity in MYCN-Amplified Neuroblastoma Cells. Toxins (Basel) 10:N/A (2018). PubMed: 29954071
  • Bian D  et al. Novel circular RNA, hsa_circ_0025039 promotes cell growth, invasion and glucose metabolism in malignant melanoma via the miR-198/CDK4 axis. Biomed Pharmacother 108:165-176 (2018). PubMed: 30219673
  • Yu X  et al. lncRNA LINC01296 regulates the proliferation, metastasis and cell cycle of osteosarcoma through cyclin D1. Oncol Rep 40:2507-2514 (2018). PubMed: 30226542
  • Shen L  et al. NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis. Oncogene 37:1759-1774 (2018). WB ; Mouse . PubMed: 29343851
  • Gao L  et al. Dual inhibition of mTORC1/2 by DCZ0358 induces cytotoxicity in multiple myeloma and overcomes the protective effect of the bone marrow microenvironment. Cancer Lett 421:135-144 (2018). WB . PubMed: 29428642
  • Li J  et al. Down-regulation of microRNA-27b promotes retinal pigment epithelial cell proliferation and migration by targeting Nox2. Pathol Res Pract 214:925-933 (2018). WB ; Human . PubMed: 29858119
  • Gu H  et al. Highly expressed histone deacetylase 5 promotes the growth of hepatocellular carcinoma cells by inhibiting the TAp63-maspin pathway. Am J Cancer Res 8:462-475 (2018). WB ; Human . PubMed: 29637001
  • Ma L  et al. Long non-coding RNA XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer. Oncotarget 8:4125-4135 (2017). WB ; Human . PubMed: 27911852
  • Fu S  et al. Lack of adiponectin and adiponectin receptor 1 contributes to benign prostatic hyperplasia. Oncotarget 8:88537-88551 (2017). PubMed: 29179455
  • Feng F  et al. Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells. Oncol Lett 14:2947-2953 (2017). PubMed: 28928832
  • Chen JL  et al. Suppression of SIK1 by miR-141 in human ovarian cancer cell lines and tissues. Int J Mol Med 37:1601-10 (2016). PubMed: 27081781
  • Lv XJ  et al. RNA-binding motif protein 5 inhibits the proliferation of cigarette smoke-transformed BEAS-2B cells through cell cycle arrest and apoptosis. Oncol Rep N/A:N/A (2016). PubMed: 26782095
  • Tian LQ  et al. MicroRNA-197 inhibits cell proliferation by targeting GAB2 in glioblastoma. Mol Med Rep N/A:N/A (2016). PubMed: 27035789
  • Wang G  et al. Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPAR? signalling pathway. Sci Rep 6:35783 (2016). WB . PubMed: 27779188
  • Mao M & Wang W SerpinE2 promotes multiple cell proliferation and drug resistance in osteosarcoma. Mol Med Rep 14:881-7 (2016). PubMed: 27221371
  • Suwei D  et al. NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin. J Hematol Oncol 8:120 (2015). Human . PubMed: 26503334

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