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Rabbit polyclonal to CDKN3
Mouse, Rat, Human
Predicted to work with:
Recombinant full length protein corresponding to Human CDKN3.
MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPG CKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCG IITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLV AACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKLAAHL SSRDSQSRSVSR
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium azide Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration.
1/50 - 1/200.
1/500 - 1/2000. Predicted molecular weight: 24 kDa.
May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
Involvement in disease
Defects in CDKN3 are found in patients with hepatocellular carcinoma (HCC) [MIM:114550].
Belongs to the protein-tyrosine phosphatase family.
Cytoplasm > perinuclear region.
Information by UniProt
Cdk associated protein phosphatase antibody
CDK2 associated dual specificity phosphatase antibody
Immunocytochemistry/ Immunofluorescence - Anti-CDKN3 antibody (ab175393)
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab175393. Blue DAPI for nuclear staining.
Western blot - Anti-CDKN3 antibody (ab175393)
Anti-CDKN3 antibody (ab175393) at 1/500 dilution + Mouse heart extract
Predicted band size: 24 kDa
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"