Anti-CDX2 antibody (ab70458)

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Overview

  • Product name

    Anti-CDX2 antibody
    See all CDX2 primary antibodies

  • Description

    Rabbit polyclonal to CDX2

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-P, IPmore details
    Unsuitable for: WB

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow, Chimpanzee, Gorilla, Orangutan, Bat

  • Immunogen

    Synthetic peptide corresponding to a region between residues 250 and 300 of Human CDX2 (according to NP_001256.1)

  • Positive control

    • 293T whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab70458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 1-4 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.

    • Target

    • Function

      Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

    • Sequence similarities

      Belongs to the Caudal homeobox family.
      Contains 1 homeobox DNA-binding domain.

    • Post-translational
      modifications

      Phosphorylation of Ser-60 mediates the transactivation capacity.

    • Cellular localization

      Nucleus.
    • Information by UniProt

    • Database links

      • Alternative names

        • Caudal type homeo box 2 antibody
        • Caudal type homeo box transcription factor 2 antibody
        • Caudal type homeobox 2 antibody
        • Caudal type homeobox protein 2 antibody
        • Caudal type homeobox transcription factor 2 antibody
        • Caudal-type homeobox protein 2 antibody
        • CDX 2 antibody
        • CDX 3 antibody
        • CDX-3 antibody
        • Cdx2 antibody
        • CDX2/AS antibody
        • CDX2_HUMAN antibody
        • CDX3 antibody
        • Homeobox protein CDX 2 antibody
        • Homeobox protein CDX-2 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDX2 antibody (ab70458)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDX2 antibody (ab70458)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling CDX2 with ab70458 at 1/1000 (1µg/ml). Detection: DAB.

      References

      This product has been referenced in:

      • Chu X  et al. Establishment and characterization of a novel cell line (cc-006cpm8) of moderately/poorly differentiated colorectal adenocarcinoma derived from a primary tumor of a patient. Int J Oncol 55:243-256 (2019). Read more (PubMed: 31115570) »
      See 1 Publication for this product

      Publishing research using ab70458? Please let us know so that we can cite the reference in this datasheet.

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