Overview

  • Product name
    Anti-CDX2 antibody [SP54]
    See all CDX2 primary antibodies
  • Description
    Rabbit monoclonal [SP54] to CDX2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human CDX2 aa 100-200 (N terminal). The exact sequence is proprietary.
    Database link: Q99626

  • Positive control
    • Human Colon carcinoma

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab101532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Antigen retrieval is recommended: Boil tissue section in 10mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Flow Cyt Use at an assay dependent concentration.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Function
    Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
  • Sequence similarities
    Belongs to the Caudal homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Post-translational
    modifications
    Phosphorylation of Ser-60 mediates the transactivation capacity.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
    • Alternative names
      • Caudal type homeo box 2 antibody
      • Caudal type homeo box transcription factor 2 antibody
      • Caudal type homeobox 2 antibody
      • Caudal type homeobox protein 2 antibody
      • Caudal type homeobox transcription factor 2 antibody
      • Caudal-type homeobox protein 2 antibody
      • CDX 2 antibody
      • CDX 3 antibody
      • CDX-3 antibody
      • Cdx2 antibody
      • CDX2/AS antibody
      • CDX2_HUMAN antibody
      • CDX3 antibody
      • Homeobox protein CDX 2 antibody
      • Homeobox protein CDX-2 antibody
      see all

    Images

    • Flow Cytometry - Anti-CDX2 antibody [SP54] (ab101532)
      Flow Cytometry - Anti-CDX2 antibody [SP54] (ab101532)

      Flow cytometric analysis of rabbit anti-CDX2 (SP54) antibody ab101532(1/100) in HT29 cells (green) compared to negative control of rabbit IgG (blue).

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDX2 antibody [SP54] (ab101532)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDX2 antibody [SP54] (ab101532)
      Staining of Human CDX2 in a Formalin/PFA-fixed paraffin-embedded section of Human Colon Carcinoma using ab101532 at a dilution of 1/100.

    References

    This product has been referenced in:
    • Chen Y  et al. 5-Aza-dC treatment induces mesenchymal-to-epithelial transition in 1st trimester trophoblast cell line HTR8/SVneo. Biochem Biophys Res Commun 432:116-22 (2013). ICC/IF ; Human . Read more (PubMed: 23376068) »

    See 1 Publication for this product

    Publishing research using ab101532? Please let us know so that we can cite the reference in this datasheet.

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