Anti-CEACAM1 + CEACAM3 + CEACAM6 antibody [YTH71.3] (ab104450)
Key features and details
- Rat monoclonal [YTH71.3] to CEACAM1+CEACAM3+CEACAM6
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2a
Overview
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Product name
Anti-CEACAM1 + CEACAM3 + CEACAM6 antibody [YTH71.3]
See all CEACAM1+CEACAM3+CEACAM6 primary antibodies -
Description
Rat monoclonal [YTH71.3] to CEACAM1+CEACAM3+CEACAM6 -
Host species
Rat -
Specificity
Recognizes Human CEACAM1. CEACAM1 is expressed by Human neutrophils and cells in some cases of colon carcinoma. Reacts with transfectants containing BGPa, NCA and CGM1a which are CEA subfamily members. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Monkey -
Immunogen
Tissue, cells or virus corresponding to Human CEACAM1+CEACAM6+CEACAM3. Human lymphocytes.
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Positive control
- Human Colon, Human Liver
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
YTH71.3 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab104450 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Cellular localization
CEACAM1: Secreted; Cell membrane and Cell membrane. Localizes to sites of cell-cell contact. CEACAM6: Cell membrane. CEACAM3: Membrane. -
Database links
- Entrez Gene: 1084 Human
- Entrez Gene: 4680 Human
- Entrez Gene: 634 Human
- Omim: 109770 Human
- Omim: 163980 Human
- Omim: 609142 Human
- SwissProt: P13688 Human
- SwissProt: P40198 Human
see all -
Form
CEACAM1: There are 11 isoforms produced by alternative splicing. Isoform 1 = BGPa; CEACAM1-4L; TM1-CEA; Isoform 2 = BGPg; CEACAM1-4C1; Isoform 3 = BGPh; CEACAM1-3; Isoform 4 = BGPi; CEACAM1-3C2; Isoform 5 = BGPy; CEACAM1-3AL; Isoform 6 = BGPb; CEACAM1-3L; TM2-CEA; Isoform 7 = BGPx; CEACAM1-1L; Isoform 8 = BGPc; CEACAM1-4S; TM3-CEA; Isoform 9 = BGPz; CEACAM1-3AS and Isoform 11 = BGPd; CEACAM1-3S.
Images
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Human Colon (formalin-fixed, paraffin-embedded) stained with ab104450 at 10 ug/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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Human Liver (formalin-fixed, paraffin-embedded) stained with ab104450 at 10 ug/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Datasheets and documents
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Datasheet download
References (0)
ab104450 has not yet been referenced specifically in any publications.