Overview

  • Product name

    Anti-CEACAM19 antibody [HY-8H10]
  • Description

    Mouse monoclonal [HY-8H10] to CEACAM19
  • Host species

    Mouse
  • Specificity

    This antibody reacts with CEACAM19.
  • Tested applications

    Suitable for: Flow Cyt, Competitive ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Genetic immunisation with cDNA encoding human CEACAM19.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    HY-8H10
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab59717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
Competitive ELISA
  • Application notes
    cELISA: 1/200 - 1/400.
    Flow Cyt: Use 1.2µg for 106 cells.
    SDS-PAGE: Use 2µg.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance

      CEACAM19 belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. Like all members of the CEACAM family, the CEACAM19 protein is a single-pass type I membrane protein and consists of a single extracellular N domain. CEACAM19 expression is ubiquitous with highest expression in prostate, uterus, fetal brain, mammary gland, adrenal gland, skeletal muscle, small intestine, and kidney.
    • Cellular localization

      Cell Membrane; Single-pass type I membrane protein .
    • Database links

    • Alternative names

      • Carcinoembryonic antigen like 1 antibody
      • Carcinoembryonic antigen related cell adhesion molecule 19 antibody
      • CEA related cell adhesion molecule 19 antibody
      • CEAL1 antibody
      • MGC105097 antibody
      see all

    Images

    • BOSC23 cells were transiently trans-fected with an expression vector encoding either CEACAM19 (red curve) or an irrelevant protein (control transfectant). Binding of ab59717 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with CEACAM19 transfected cells.

    References

    This product has been referenced in:

    • Kobayashi M  et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107:1745-53 (2012). Read more (PubMed: 23099808) »
    See 1 Publication for this product

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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